compounds |
S. a |
B. s |
S. c |
C. a |
M. p |
A. n |
IC50 |
成 分 名 |
抗菌活性(MIC) |
GTase阻害 |
Licochalcone A(1) |
1.56 |
3.13 |
x |
x |
12.5 |
x |
28 |
Licochalcone B(1) |
100 |
100 |
x |
x |
x |
x |
40 |
Licochalcone C(1) |
6.25 |
12.5 |
50 |
x |
12.5 |
x |
23 |
Licochalcone D(1) |
50 |
50 |
50 |
100 |
x |
x |
10 |
Echinatin(1) |
25 |
25 |
x |
x |
x |
x |
x |
5'-Prenyllicodione(2) |
6.25 |
12.5 |
100 |
100 |
50 |
x |
x |
Glycyrdione A(2) |
25 |
100 |
x |
x |
x |
x |
x |
Glycyrdione C(2) |
x |
x |
x |
x |
x |
x |
6 |
7,4'-diOH-flavone(3) |
x |
x |
x |
x |
x |
x |
x |
Licoflavone A(3) |
x |
x |
x |
x |
x |
x |
x |
Licoflavone B(3) |
x |
x |
x |
x |
x |
x |
32 |
Licoflavone C(3) |
x |
x |
x |
x |
x |
x |
x |
Glabrol(4) |
12.5 |
100 |
x |
x |
x |
x |
37 |
Formononetin(5) |
25 |
25 |
x |
x |
x |
x |
x |
Licoisoflavone A(5) |
50 |
x |
x |
x |
x |
x |
32 |
Licoisoflavone B(5) |
6.25 |
12.5 |
x |
x |
25 |
x |
x |
Glabrone(5) |
x |
x |
x |
x |
x |
x |
x |
Caffeicacid ester(6) |
x |
x |
x |
x |
x |
x |
x |
(備考)
(1)Retrochalcones; (2)Dibenzoylmethanes; (3)Flavones; (4)Flavanone; (5)Isoflavones; (6)Phenylpropanoid;
S. a: Staphylococcus aureus; B. s: Bacillus subtilis; S. c: Saccharomyces cerevisiae;
C. a: Candida albicans; M. p: Mucor pusillus; A. n: Aspergillus niger
MIC、IC50いずれも単位はμg/mL; x: >100μg/mL