compounds S. a B. s S. c C. a M. p A. n IC50
成 分 名 抗菌活性(MIC) GTase阻害
Licochalcone A(1) 1.56 3.13 x x 12.5 x 28
Licochalcone B(1) 100 100 x x x x 40
Licochalcone C(1) 6.25 12.5 50 x 12.5 x 23
Licochalcone D(1) 50 50 50 100 x x 10
Echinatin(1) 25 25 x x x x x
5'-Prenyllicodione(2) 6.25 12.5 100 100 50 x x
Glycyrdione A(2) 25 100 x x x x x
Glycyrdione C(2) x x x x x x 6
7,4'-diOH-flavone(3) x x x x x x x
Licoflavone A(3) x x x x x x x
Licoflavone B(3) x x x x x x 32
Licoflavone C(3) x x x x x x x
Glabrol(4) 12.5 100 x x x x 37
Formononetin(5) 25 25 x x x x x
Licoisoflavone A(5) 50 x x x x x 32
Licoisoflavone B(5) 6.25 12.5 x x 25 x x
Glabrone(5) x x x x x x x
Caffeicacid ester(6) x x x x x x x
(備考)
(1)Retrochalcones; (2)Dibenzoylmethanes; (3)Flavones; (4)Flavanone; (5)Isoflavones; (6)Phenylpropanoid;
S. a: Staphylococcus aureus; B. s: Bacillus subtilis; S. c: Saccharomyces cerevisiae;
C. a: Candida albicans; M. p: Mucor pusillus; A. n: Aspergillus niger
MIC、IC50いずれも単位はμg/mL; x: >100μg/mL